SYBR Green qPCR primers for detecting mouse Nlrp3 (NLR family, pyrin domain containing 3) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Mouse Nlrp3 qPCR Primer Set – NLR family, pyrin domain containing 3
Also known as: AGTAVPRL, AII/AVP, Cias1, FCAS, FCU, MWS, Mmig1, NALP3, Pypaf1
About this gene: Enables several functions, including ATP hydrolysis activity; phosphatidylinositol-4-phosphate binding activity; and signaling adaptor activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of immune response; and response to bacterium. Acts upstream of or within acute inflammatory response; defense response to virus; and regulation of inflammatory response. Located in interphase microtubule organizing center; mitochondrion; and nucleus. Part of NLRP3 inflammasome complex. Is active in membrane. Is expressed in central nervous system and retina. Used to study CINCA Syndrome; familial cold autoinflammatory syndrome 1; and metabolic dysfunction-associated steatotic liver disease. Human ortholog(s) of this gene implicated in CINCA Syndrome; Muckle-Wells syndrome; autosomal dominant nonsyndromic deafness 34; familial cold autoinflammatory syndrome 1; and urticaria. Orthologous to human NLRP3 (NLR family pyrin domain containing 3).
Gene details: NCBI Gene ID: 216799; Chromosome location: 11 37.73 cM
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Mouse PCR Primer Sets.