SYBR Green qPCR primers for detecting mouse Cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Mouse Cacna1c qPCR Primer Set – calcium channel, voltage-dependent, L type, alpha 1C subunit
Also known as: Cav1.2, Cchl1a1, D930026N18Rik, MBC, MELC-CC
About this gene: Enables enzyme binding activity and voltage-gated calcium channel activity involved in cardiac muscle cell action potential. Involved in positive regulation of adenylate cyclase activity and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Acts upstream of or within several processes, including adult walking behavior; regulation of blood circulation; and secretion by cell. Located in several cellular components, including T-tubule; Z disc; and dendritic shaft. Part of caveolar macromolecular signaling complex and voltage-gated calcium channel complex. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and heart. Used to study Timothy syndrome. Human ortholog(s) of this gene implicated in Brugada syndrome 3; Timothy syndrome; long QT syndrome 8; and neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures. Orthologous to human CACNA1C (calcium voltage-gated channel subunit alpha1 C).
Gene details: NCBI Gene ID: 12288; Chromosome location: 6 55.86 cM
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Mouse PCR Primer Sets.