SYBR Green qPCR primers for detecting mouse Trem2 (triggering receptor expressed on myeloid cells 2) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Mouse Trem2 qPCR Primer Set – triggering receptor expressed on myeloid cells 2
Also known as: TREM-2, Trem2a, Trem2b, Trem2c
About this gene: The Trem2 protein is part of the immunoglobulin and lectin-like superfamily and acts as part of the innate immune system. The Trem2 protein associates with the adaptor protein Dap-12 and recruits multiple factors, such as kinases and phospholipase C-gamma, to form a receptor signaling complex that activates myeloid cells, including dendritic cells and microglia. In humans homozygous loss-of-function mutations in Trem2 cause Nasu-Hakola disease and mutations in Trem2 may be risk factors to the development of Alzheimer's disease.
Gene details: NCBI Gene ID: 83433; UniProt: Q99NH8; Chromosome location: 17 C|17 23.99 cM
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Mouse PCR Primer Sets.