SYBR Green qPCR primers for detecting mouse Insr (insulin receptor, also called IR) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Mouse Insr qPCR Primer Set – insulin receptor
Also known as: 4932439J01Rik, CD220, D630014A15Rik, IR, IR-A, IR-B
About this gene: Insr belongs to the receptor tyrosine kinase family of transmembrane signaling proteins that play important roles in cell differentiation, growth and metabolism. The encoded preproprotein undergoes proteolytic processing to generate alpha and beta chains that form a disulfide-linked heterodimer which, in turn homodimerizes to form a mature, functional receptor. Mice lacking the Insr protein develop severe hyperglycemia and hyperketonemia, and die within a couple of days after birth as a result of diabetic ketoacidosis.
Gene details: NCBI Gene ID: 16337; UniProt: P15208; Chromosome location: 8 A1.1|8 1.82 cM
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Mouse PCR Primer Sets.