Human DENND2B qPCR primer set for DENN domain containing 2B

DENND2B (Human)
Item# VHPS-8902
$24.95

Product Description

SYBR Green qPCR primers for detecting human DENND2B (DENN domain containing 2B) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.

Human DENND2B qPCR Primer Set – DENN domain containing 2B

Also known as: HTS1, ST5, p126

About this gene: DENND2B was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The DENND2B protein contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. The DENND2B protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells.

Gene details: NCBI Gene ID: 6764; HGNC ID: HGNC:11350; UniProt: P78524; RefSeq (MANE Select): NM_213618.2; Chromosome location: 11p15.4

What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.

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