SYBR Green qPCR primers for detecting human SOST (sclerostin) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human SOST qPCR Primer Set – sclerostin
Also known as: CDD, DAND6, SOST1, VBCH
About this gene: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein antagonists. Loss-of-function mutations in SOST are linked to an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of SOST, which causes reduced sclerostin expression, is linked to a milder form of the disorder called van Buchem disease.
Gene details: NCBI Gene ID: 50964; HGNC ID: HGNC:13771; UniProt: Q9BQB4; RefSeq (MANE Select): NM_025237.3; Chromosome location: 17q21.31
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets.