SYBR Green qPCR primers for detecting human PON1 (paraoxonase 1) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human PON1 qPCR Primer Set – paraoxonase 1
Also known as: ESA, MVCD5, PON
About this gene: PON1 belongs to the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in PON1 may be linked to coronary artery disease and diabetic retinopathy.
Gene details: NCBI Gene ID: 5444; HGNC ID: HGNC:9204; UniProt: P27169; RefSeq (MANE Select): NM_000446.7; Chromosome location: 7q21.3
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets.