SYBR Green qPCR primers for detecting human LDLR (low density lipoprotein receptor) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human LDLR qPCR Primer Set – low density lipoprotein receptor
Also known as: LDLCQ2
About this gene: The low density lipoprotein receptor gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. The LDLR protein is normally bound at the cell membrane, where it binds low density lipoprotein/cholesterol and is taken into the cell. Lysosomes release the cholesterol, which is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting step in cholesterol synthesis.
Gene details: NCBI Gene ID: 3949; HGNC ID: HGNC:6547; UniProt: P01130; RefSeq (MANE Select): NM_000527.5; Chromosome location: 19p13.2
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets.