SYBR Green qPCR primers for detecting human DPYD (dihydropyrimidine dehydrogenase, also called DPD) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human DPYD qPCR Primer Set – dihydropyrimidine dehydrogenase
Also known as: DHP, DHPDHASE, DPD, DYPD
About this gene: The DPYD protein is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in DPYD result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism linked to thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.
Gene details: NCBI Gene ID: 1806; HGNC ID: HGNC:3012; UniProt: Q12882; RefSeq (MANE Select): NM_000110.4; Chromosome location: 1p21.3
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets.