SYBR Green qPCR primers for detecting human APPL2 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2, also called Dip13-beta) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human APPL2 qPCR Primer Set – adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
Also known as: DIP13B
About this gene: The APPL2 protein is one of two effectors of the small GTPase RAB5A/Rab5, which are involved in a signal transduction pathway. Both effectors contain an N-terminal Bin/Amphiphysin/Rvs domain, a central pleckstrin homology domain, and a C-terminal phosphotyrosine binding domain, and they bind the Rab5 through the BAR domain. They are linked to endosomal membranes and can be translocated to the nucleus in response to the EGF stimulus.
Gene details: NCBI Gene ID: 55198; HGNC ID: HGNC:18242; UniProt: Q8NEU8; RefSeq (MANE Select): NM_018171.5; Chromosome location: 12q23.3
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets.