SYBR Green qPCR primers for detecting human COMT (catechol-O-methyltransferase) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human COMT qPCR Primer Set – catechol-O-methyltransferase
Also known as: HEL-S-98n
About this gene: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation leads to one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease.
Gene details: NCBI Gene ID: 1312; HGNC ID: HGNC:2228; UniProt: P21964; RefSeq (MANE Select): NM_000754.4; Chromosome location: 22q11.21
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets.