SYBR Green qPCR primers for detecting human CIC (capicua transcriptional repressor) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human CIC qPCR Primer Set – capicua transcriptional repressor
Also known as: MRD45
About this gene: The CIC protein is an ortholog of the Drosophila melanogaster capicua gene, and belongs to the high mobility group-box superfamily of transcriptional repressors. The CIC protein contains a conserved HMG domain that is involved in DNA binding and nuclear localization, and a conserved C-terminus. Studies suggest that the N-terminal region of this protein interacts with Atxn1, to form a transcription repressor complex, and in vitro studies suggest that polyglutamine-expansion of ATXN1 may alter the repressor activity of this complex.
Gene details: NCBI Gene ID: 23152; HGNC ID: HGNC:14214; UniProt: Q96RK0; RefSeq (MANE Select): NM_001386298.1; Chromosome location: 19q13.2
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets.