SYBR Green qPCR primers for detecting human NLRP3 (NLR family pyrin domain containing 3, also called CLR1.1) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human NLRP3 qPCR Primer Set – NLR family pyrin domain containing 3
Also known as: AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCAS1, FCU, KEFH, MWS
About this gene: NLRP3 encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site domain, and a leucine-rich repeat motif. The NLRP3 protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and belongs to the NLRP3 inflammasome complex. This complex acts as an upstream activator of NF-kappaB signaling, and it is involved in the regulation of inflammation, the immune response, and apoptosis.
Gene details: NCBI Gene ID: 114548; HGNC ID: HGNC:16400; UniProt: Q96P20; RefSeq (MANE Select): NM_001243133.2; Chromosome location: 1q44
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets, or profile NLRP3 alongside related genes with our Human Pan Cell Death Primer Library.