SYBR Green qPCR primers for detecting human CCM2 (CCM2 scaffold protein, also called Malcavernin) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human CCM2 qPCR Primer Set – CCM2 scaffold protein
Also known as: C7orf22, OSM, PP10187
About this gene: CCM2 encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells.
Gene details: NCBI Gene ID: 83605; HGNC ID: HGNC:21708; UniProt: Q9BSQ5; RefSeq (MANE Select): NM_031443.4; Chromosome location: 7p13
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets.