SYBR Green qPCR primers for detecting human CCND1 (cyclin D1) gene expression by real-time PCR. Each set comes with primer sequences and reaction conditions.
Human CCND1 qPCR Primer Set – cyclin D1
Also known as: BCL1, D11S287E, PRAD1, U21B31
About this gene: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of human cancers.
Gene details: NCBI Gene ID: 595; HGNC ID: HGNC:1582; RefSeq (MANE Select): NM_053056.3; Chromosome location: 11q13.3
What you get: Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with H2O as needed prior to use. This amount is sufficient for 1,000 PCR reactions of 20 µl, assuming a final primer concentration of 0.1 µM.
Browse all Human PCR Primer Sets.