Human Tumor Invasion/Metastasis Primer Library

Contains 88 primer sets directed against tumor invasion/metastasis genes and 8 housekeeping gene primer sets.

Provided in a 96-well microplate (20 ul - 10 uM)

Perform up to 100 PCR arrays (based on 20 ul assay volume per reaction)

Just add cDNA template and SYBR green master mix



GENE LIST:

ADAMTS1 ADAM metallopeptidase

ALDH3A1 Aldehyde dehydrogenase 3 family, memberA1

ANGPT1 Angiopoietin 1

ANGPTL4 Angiopoietin-like 4

CASP8 Caspase 8, apoptosis-related cysteine peptidase

CCNE2 Cyclin E2

CCR7 Chemokine (C-C motif) receptor 7

CD44 CD44 molecule (Indian blood group)

CD82 CD82 antigen

CDH1 Cadherin 1, type 1, E-cadherin (epithelial)

CDH11 Cadherin 11, type 2, OB-cadherin (osteoblast)

CDH2 Cadherin 2, type 1, N-cadherin

CDH6 Cadherin 6

CLDN7 Claudin 7

COL1A1 Collagen, type I, alpha 1

COL4A2 Collagen, type IV, alpha 2

COL6A1 Collagen, type VI, alpha 1

CSF1 Colony stimulating factor 1 (macrophage)

CSF3 Colony stimulating factor 3 (granulocyte)

CST7 Cystatin F (leukocystatin)

CTGF Connective tissue growth factor

CTSB Cathepsin B

CTSD Cathepsin D

CTSK Cathepsin K

CTSL1 Cathepsin L-like 3

CXCL1 Chemokine (C-X-C motif) ligand 1

CXCL12 Chemokine (C-X-C motif) ligand 12

CXCR4 Chemokine (C-X-C motif) receptor 4

CXCR6 Chemokine (C-X-C motif) receptor 6

DRG1 Developmentally regulated GTP binding protein 1

EREG Epiregulin

FGF8 Fibroblast growth factor 8 (androgen-induced)

FLT1 Fms-related tyrosine kinase

FLT4 Fms-related tyrosine kinase 4

GPI Glucose phosphate isomerase

GSN Gelsolin (amyloidosis, Finnish type)

HGF Hepatocyte growth factor (hepapoietin A; scatter factor)

HIF1A Hypoxia inducible factor 1, alpha subunit

HMGB1 High-mobility group box 1

ID1 Inhibitor of DNA binding 1

IGFBP7 Insulin-like growth factor binding protein 7

IL13RA2 Interleukin 13 receptor, alpha 2

ISG20 Interferon stimulated exonuclease gene 20kDa

JAG1 Jagged 1 (Alagille syndrome)

KISS1 KiSS-1 metastasis-suppressor

KLRC2 Killer cell lectin-like receptor subfamily C, member 2

KYNU Kynureninase (L-kynurenine hydrolase)

LTBP1 Latent transforming growth factor beta binding protein 1

MAP2K4 Mitogen-activated protein kinase kinase 4

MAP2K5 Mitogen-activated protein kinase kinase 5

MAP2K7 Mitogen-activated protein kinase kinase 7

MCAM Melanoma cell adhesion molecule

MET Met proto-oncogene (hepatocyte growth factor receptor)

METAP2 Methionyl aminopeptidase 2

MMP1 Matrix metallopeptidase 1 (interstitial collagenase)

MMP10 Matrix metallopeptidase 10 (stromelysin 2)

MMP11 Matrix metallopeptidase 11 (stromelysin 3)

MMP13 Matrix metallopeptidase 13 (collagenase 3)

MMP14 Matrix metallopeptidase 14 (membrane-inserted)

MMP2 Matrix metallopeptidase 2

MMP7 Matrix metallopeptidase 7 (matrilysin, uterine)

MYC V-myc myelocytomatosis viral oncogene homolog

NEDD9 Neural precursor cell expressed, dev. down- regulated 9

NF2 Neurofibromin 2 (merlin)

NME1 Non-metastatic cells 1, protein (NM23A)

NME2 Non-metastatic cells 2, protein

NME4 Non-metastatic cells 4, protein

PAX5 Paired box 5

PDGFA Platelet-derived growth factor alpha polypeptide

PLAUR Plasminogen activator, urokinase receptor

PTGS2 Prostaglandin-endoperoxide synthase 2

RUNX1 Runt-related transcription factor 1

SERPINE1 Serpin peptidase inhibitor, clade E

SERPINB5 Serpin peptidase inhibitor, clade B5

SOX4 SRY (sex determining region Y)-box 4

SPARC Secreted protein, acidic, cysteine-rich (osteonectin)

SPP1 Secreted phosphoprotein 1

SRC V-src sarcoma viral oncogene homolog (avian)

SYK Spleen tyrosine kinase

TFF1 Trefoil factor 1

TGFB1 Transforming growth factor, beta 1

TIMP1 TIMP metallopeptidase inhibitor 1

TIMP2 TIMP metallopeptidase inhibitor 2

TIMP3 TIMP metallopeptidase inhibitor 3

TIMP4 TIMP metallopeptidase inhibitor 4

TNC Tenascin C (hexabrachion)

TP53 Tumor protein p53

VEGFA Vascular endothelial growth factor A

ACTB Actin, beta

B2M Beta-2-microglobulin

GAPD Glyceraldehyde-3-phosphate dehydrogenase

GUSB Glucuronidase, beta

HPRT1 Hypoxanthine phosphoribosyltransferase 1

PGK Phosphoglycerate kinase 1

PPIA Peptidylprolyl isomerase A

RPL13A Ribosomal protein L13a